TOPICAL & SYSTEMIC CHEMOTHERAPY
Chemotherapy targets the tumor with chemotherapy drugs, which are administered either topically (as a cream that is applied to the area) or by IV or pills (systemic). Topical chemotherapy is usually used for low-risk squamous cell carcinomas because it doesn't always penetrate all layers of skin, nor does it leave tissue that can be biopsied. Topical chemotherapy may also be used for superficial basal cell carcinomas that are particularly responsive to these drugs.